Opalescence™ PF 10%, 15%, 20%, 35%, and 45%

Carbamide Peroxide with Potassium Nitrate and Fluoride

For use with customized take-home whitening trays, Opalescence PF teeth whitening gel offers many options for patients. With its easy syringe delivery, Opalescence PF whitening gel is easily customizable for each patient’s individual situation. The gel contains 20% water to prevent dehydration, and the sticky, viscous formula helps keep the gel and tray in place. With five concentrations and three flavors, patients can completely customize their whitening experience.

  • Opalescence teeth whitening gel contains PF (potassium nitrate and fluoride)
  • Opalescence gel is effective in helping reduce shade relapse as compared to competitor tooth whitening products.1
  • Opalescence whitening gel is made up of at least 20% water which helps prevent dehydration.
  • Five concentrations for treatment flexibility
  • Three flavors: Mint, Melon, and Regular
  • Day or night wear
  • Sticky, viscous gel won’t migrate to soft tissues and ensures tray stays securely in place
  • Vegan—no animal products used
  • Certified gluten free
  • Certified kosher


Opalescence PF
Opalescence PF

The #1 Professional Teeth Whitening Brand on the Planet

If your patients are looking for the best teeth whitening experience and results, Opalescence PF teeth whitening can deliver. It is used with customized teeth whitening trays to provide the personalized approach that patients want, while the powerful teeth whitening gel gives them the results they deserve. With over 30 years of experience, more than 50 teeth whitening awards earned, and over 100 million smiles brightened, Opalescence teeth whitening is the #1 professional teeth whitening brand on the planet for a reason.

Opalescence Go
Global Whitening Leader

Opalescence PF teeth whitening's easy syringe delivery, five concentrations of carbamide peroxide (10%, 15%, 20%, 35%, and 45%), and three great-tasting flavors (Mint, Melon, and Regular) allow for maximum treatment flexibility based on your patient’s needs. Opalescence PF teeth whitening gel is vegan—no animal products are used. It is also certified gluten free and certified kosher, so it fits in with the lifestyles and beliefs of patients from diverse backgrounds.

Gluten Free
Opalescence PF Before and After Opalescence PF model
Opalescence PF Tray

The Best Way To Whiten Teeth

For over 30 years Opalescence teeth whitening systems have helped patients get bright white smiles in safe, trusted, and reliable ways. Our products whiten teeth chemically, using hydrogen peroxide or carbamide peroxide, and don’t rely on LED teeth whitening lights, activated charcoal, or other fads.

The carbamide peroxide in Opalescence PF teeth whitening gel whitens teeth by chemically removing discoloration deep in the enamel and dentin. Our original whitening gel formula is also sticky and viscous, preventing the gel from migrating during treatment and helping to keep the tray in place. This results in a whitening treatment that is more comfortable and effective, which means the patient receives the best teeth whitening experience possible.

Opalescence PF Tray

At-Home Teeth Whitening Done Right

Opalescence PF teeth whitening offers patients a personalized professional teeth whitening experience in the comfort of their own home. The customized whitening trays are tailored to the patient’s smile, enhancing patient comfort and providing them the attention their smile deserves. Its efficient syringe delivery is simple to use with the custom trays and allows for the patient to dispense just the right amount of whitening gel necessary for each application. Depending on the concentration used, Opalescence PF teeth whitening can be worn day or night to better fit the patient’s lifestyle.

Opalescence PF Day or Night

Create an At-Home Teeth Whitening Kit for Your Patients

While each Opalescence teeth whitening kit is effective as a stand-alone teeth whitening treatment, many patients benefit from using a combination of products to meet their needs. Because each Opalescence teeth whitening product works in combination with the others, it is easy to create a customized teeth whitening kit for any patient to take home. For example, Opalescence PF whitening is a great way to follow-up an Opalescence™ Boost™ in-office whitening treatment and go perfectly with the daily use of Opalescence™ Whitening Toothpaste.

Opalescence PF model Opalescence PF model
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Technical Details

Superior Stability

Opalescence teeth whitening products are among the most stable whitening products in the industry, each maintaining virtually all of its effectiveness over the course of its shelf life. Because delivery times vary depending on the location of each particular dental office, Opalescence whitening products are formulated with transit time in mind. Although shelf life is ultimately dependent on how each product is stored, our teeth whiteners will remain stable even after being shipped across the country.2

Formulated with High Water Content

Many whitening products on the market dehydrate teeth, resulting in uncomfortable sensitivity for patients. Opalescence PF teeth whitening gel is made up of at least 20% water content which prevents dehydration. Opalescence whitening gel is effective in helping prevent shade relapse as compared to competitor teeth whitening products.4

Sweetened with Xylitol

Opalescence PF teeth whitening gel is sweetened with xylitol which may reduce the risk of tooth decay.

Contains PF

Opalescence PF teeth whitening gel contains PF (potassium nitrate and fluoride) for patient comfort.

Perfectly Balanced pH

Because teeth whitening gel can be in the mouth for several hours at a time, it’s important to use a product with a pH that closely matches the natural pH of a patient’s saliva. When patients whiten using products that contain carbamide peroxide, like Opalescence PF whitening, the pH level of the mouth rises to a neutral level (between 7 and 8).3

Made in the USA from Globally Sourced Materials

Opalescence teeth whitening gels, trays, syringes, and toothpastes are manufactured at Ultradent’s facility in Utah from globally sourced materials. By purchasing products manufactured in the USA, you are supporting our nation’s economy and helping to provide jobs to hundreds of Americans who take pride in what they do.


Before and After Opalescence Whitening PF


Before whitening. (Photo courtesy of Dr. Robert Nixon)


Upper teeth after five nights of treatment, approximately 40 hours. (Photo courtesy of Dr. Robert Nixon)


Heavy tetracycline discolorations. This whitening process can require a whitening treatment that lasts from several weeks to months.


After whitening with Opalescence gel.


A 12-year-old before whitening.


After five nights of whitening.


Moderate to advanced tetracycline stains.


Improvement in two weeks. With tetracycline stains, treatment can require two to six months.⁵


Opalescence PF Whitening Patient Instructions

See Instructions for Use for complete instructions, warnings, and precautions.

Step 1

Express one continuous bead of gel approximately halfway up the facial side of the tray from molar to molar. This should use about 1/2 to 1/3 of a syringe per tray.

Step 2

Insert the tray in your mouth and lightly tap it to adapt the sides to your teeth. Wear time depends on which concentration of Opalescence whitening you use.

  • Opalescence PF 10%: 8–10 hours or overnight
  • Opalescence PF 15%: 4–6 hours
  • Opalescence PF 20%: 2–4 hours
  • Opalescence PF 35%: 30-60 minutes
  • Opalescence PF 45%: 15-30 minutes

If you experience any significant sensitivity, stop your treatment and talk to your dentist.

Step 3

Remove excess gel with a soft toothbrush.

Step 4

Clean tray with soft toothbrush and water. Store in tray case provided.


"​We have tried other whitening products in the office and have found that Opalescence has had the most well received results among our patients and staff. The decreased sensitivity, quick results, and the brighter whiter outcomes are just a few of the qualities Opalescence holds that truly set this product apart from all others."

Dr. Keith Jaeschke, DDS – Morris, IL

Frequently Asked Questions

  • How does teeth whitening work?

    Opalescence whitening gels contain an active whitening ingredient—either carbamide peroxide or hydrogen peroxide. Peroxide gels break down into water, oxygen, and reactive oxygen molecules. These reactive oxygen molecules treat both the enamel and the dentin, oxidizing the bonds of discolored stain molecules. By changing the stained molecules, the tooth becomes lighter.6

    Reactive oxygen molecules permeate the entire tooth, so there is no need for the whitening agent to be in contact with every surface of the tooth for the entire tooth to be whitened.6

  • Will teeth whitening affect bond strength?

    Even though whitening agents release a great amount of oxygen into the tooth, existing bonds are not weakened.7,8

    If whitening before bonding, allow a period of 7–10 days after whitening. The high concentration of oxygen in the tooth could significantly and adversely affect polymerization of the resins.9,10
  • How long do teeth whitening results last?

    Teeth whitening results are very stable, but depending on the patient’s nutrition and lifestyle habits, the procedure may need to be redone periodically. Due to the safety of the teeth whitening agents, this should not concern the dentist or patient.
  • Will teeth whitening cause sensitivity?

    Tooth sensitivity can occur as a result of whitening. If sensitivity occurs, it is transient and disappears after the completion of whitening treatments. If desensitizing treatments are desired, we recommend the use of UltraEZ desensitizing gel or Enamelast fluoride varnish. Opalescence Whitening Toothpaste Sensitivity Formula can also be used to help to prevent or lessen sensitivity if it occurs.

Research & Studies

Carbamide peroxide whitening of nonvital single discolored teeth: case reports.

Caughman WF, Frazier KB, Haywood VB. Carbamide peroxide whitening of nonvital single discolored teeth: case reports.

http://www.ncbi.nlm.nih.gov/pubmed/10356567Caughman WF, Frazier KB, Haywood VB.
  1. Grobler, S.R., et al. A Clinical Study of the Effectiveness of Two Different 10% Carbamide Peroxide Bleaching Products: A 6-Month Follow-up; Int J Dent. May 5, 2011: 167525; doi: 10.1155/2011/167525.
  2. Data on file.
  3. Haywood, VB. Orthodontic caries control and bleaching. Inside Dentistry. April 2010;2–6.
  4. Grobler, S.R., et al. A Clinical Study of the Effectiveness of Two Different 10% Carbamide Peroxide Bleaching Products: A 6-Month Follow-up; Int J Dent. May 5, 2011: 167525; doi: 10.1155/2011/167525.
  5. Haywood VB, Leonard RH, Dickinson GL. Efficacy of six months of nightguard vital bleaching tetracycline-stained teeth. J Esthet Dent. 1997;9(1):13-19.
  6. Kwon SR, Wertz PW. Review of the Mechanism of Tooth Whitening. J Esthet Restor Dent. 2015 Sep-Oct;27(5):240-57.
  7. Klukowska M, White DJ, Kozak KM, Zoladz JR, Baker RA, Garcia-Godoy F, et al. Effect of bleach on microleakage of Class V composite restorations. J Dent Res. 85(Spec Iss B):0035, 2006 (www.dentalresearch.org).
  8. Angerame D, Garaffa S, Maglione M, Di Lenarda R, De Stefano Dorigo E. Effect of in-office bleaching on Class V composite restorations seal. J Dent Res. 84(Spec Iss A):3013, 2005 (www.dentalresearch.org).
  9. Wilson D, Xu C, Hong L, Wang Y. Effects of clinical factors during tooth whitening on enamel. J Dent Res. 86(Spec Iss A):2632, 2007 (www.dentalresearch.org).
  10. Lim B-S, Ryu I, Lee Y-K, Rhee S-H, Yang H-C, Ahn S-J et al. Effect of bleaching agent on shear bond strength to dentin. J Dent Res. 85(Spec Iss B):0036, 2006 (www.dentalresearch.org).